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US Vice-President Kamala Harris - who's expected to be the Democratic nominee for November's presidential election - has held what she called "frank and constructive" talks with Israeli Prime Minister Benjamin Netanyahu.
Striking a tougher tone than President Joe Biden, Harris said she made clear her "serious concerns" about casualties in Gaza, telling Netanyahu how Israel defended itself mattered, reports BBC.
"It is time for this war to end," she said after their face-to-face talks at the White House.
Ms Harris also stressed the need for a path to a two-state solution, while calling on Americans to be aware of "nuance" on the conflict.
Earlier on Thursday, Mr Netanyahu met Mr Biden, who stepped down from his re-election campaign on Sunday.
Mr Netanyahu's meetings at the White House came a day after he gave a fiery speech to Congress, vowing “total victory” against Hamas, as thousands of pro-Palestinian protesters demonstrated outside.
The prime minister faces pressure both at home and abroad to bring an end to the Israel-Gaza war, now in its ninth month.